Sailor Piece Runes Tier List – Best Rune Buffs

My tier list ranks all Sailor Piece Runes, taking their buffs into account in terms of usefulness overall in battle. Got some spare Race Rerolls in Sailor Piece? My Sailor Piece Races guide might come in handy before you spend them.

Sailor Piece Runes Tier List

Runes are an optional, but useful, item to equip in Sailor Piece. In my rankings, I’ve made sure to list their Base and Maximum buffs.

S Tier

Inferno Rune
Rarity: MythicalBuffs:
Base:
Deal 70% Burn DMG (scales off of your DMG stat)
Burn DMG lasts for 4 seconds

Maximum:
Deal 104% Burn DMG (scales off of your DMG stat)
Burn DMG lasts for 4 seconds

How to Get:
Rare drop from the Rune Dungeon

Blood Rune
Rarity: MythicalBuffs:
Base:
Deal 65% Blood DMG (scales off of your DMG stat)
Blood DMG lasts for 5 seconds

Maximum:
Deal 97% Blood DMG (scales off of your DMG stat)
Blood DMG lasts for 5 seconds

How to Get:
Rare drop from the Rune Dungeon

A Tier

Guardian Rune
Rarity: EpicBuffs:
Base:
Maximum HP increases by 39% (a Multiplier of 1.39x)
Maximum:
Maximum HP increases by 59% (a Multiplier of 1.59x)

How to Get:
Rare drop from the Rune Dungeon

Wrath Rune
Rarity: MythicalBuffs:
Base:
DMG increases by 40% (a Multiplier of 1.4x)
Maximum:
DMG increases by 59% (a Multiplier of 1.59x)

How to Get:
Rare drop from the Rune Dungeon

B Tier

Frost Rune
Rarity: LegendaryBuffs:
Base:
Inflict enemies with Freeze for 2 secondsDeal 30% Impact DMG (scales off of your DMG stat)
Maximum:
Inflict enemies with Freeze for 3 secondsDeal 44% Impact DMG (scales off of your DMG stat)

How to Get:
Rare drop from the Rune Dungeon

Destruction Rune
Rarity: LegendaryBuffs:
Base:
DMG increases by 25% (a Multiplier of 1.25x)
Maximum:
DMG increases by 37% (a Multiplier of 1.37x)

How to Get:
Rare drop from the Rune Dungeon

C Tier

Suppression Rune
Rarity: RareBuffs:
Base:
DMG Reduction increases by 10%
Maximum:
DMG Reduction increases by 15%

How to Get:
Rare drop from the Rune Dungeon

D Tier

Fortune Rune
Rarity: MythicalBuffs:
Base:
Luck increases by 10%
Maximum:
Luck increases by 15%

How to Get:
Rare drop from the Rune Dungeon

How to Get Runes

The only way to get Runes in Sailor Piece is by delving into Rune Dungeons. Each NPC you defeat has a chance to drop a random Rune. Runes of a higher rarity are much less likely to appear.

How to Enter the Rune Dungeon

The Rune Dungeon can be entered by using a Dungeon Key. This Epic rarity item is obtainable via World Bosses, but not the Shadow World Boss, so keep that in mind. Take note that Dungeon Keys are not a guaranteed drop when defeating World Bosses.

The World Bosses that drop Dungeon Keys are:

Saber
Location: Boss Island
Sukuna
Location: Shibuya Station
Gojo
Location: Shibuya Station
Yuji
Location: Shibuya Station
Jinwoo
Location: Sailor Island
Ragna
Location: Christmas Island (limited-time seasonal event)
Aizen
Location: Hueco Mundo
Qin Shi
Location: Boss Island
Alucard
Location: Sailor Island
Strongest in History
Location: Shinjuku Island
Strongest of Today
Location: Shinjuku Island
Ichigo
Location: Boss Island
Rimuru
Location: Slime Island
Madoka
Location: Valentine Island (limited-time seasonal event)
Gilgamesh
Location: Boss Island

There’s also a rare chance for Dungeon Keys to appear in chests.

Beating the Rune Dungeon

The Rune Dungeon features 15 waves in total. You can choose between 4 difficulties, including Easy, Medium, Hard, and Extreme. The higher the difficulty you set, the higher the drop chance.

There are specific mobs that appear within the Rune Dungeon, which are:

RaidersCommandersBlack KnightsKnights

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